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Endocrine disruptors
Endocrine disruptors (EDCs) are chemical substances or compounds that influence the hormone system of living organisms and can therefore disrupt important biological processes. The endocrine system regulates essential functions such as growth, reproduction, metabolism and immune defence through the action of hormones produced in specialised glands such as the thyroid, adrenal glands and gonads. The assessment of EDCs is crucial to identify potential risks to health and the environment and to fulfil regulatory requirements.
Our test portfolio for the following product groups:
Chemicals, agrochemicals, SVHC, biocides
- In vitro human estrogen receptor-alpha transcriptional activation assay OECD 455 / OPPTS 890.1300
- In vitro H295R steroidogenesis assay OECD 456 / OPPTS 890.1550
- In vitro stably transfected human androgen receptor transcriptional activation assay OECD 458
- In vitro human recombinant estrogen receptor (hrER) OECD 493 / OPPTS 890
- In vitro androgen receptor binding (rat prostate cytosol) OPPTS 890.1150
- In vitro aromatase assay OPPTS 890.1200
- In vitro thyroperoxydase (TPO) function assay (thyroid mikosoms) OECD scoping doc. 207
- In vitro Natriumiodid Symporter (NIS) Aktivitätsassay OECD scoping doc. 207
- In vivo uterotrophic bioassay in rodents (UT Assay) OECD 440 / OPPTS 890.1600
- In vivo Hershberger bioassay in rat (H Assay) OECD 441 / OPPTS 890.1400
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- + 49 30 843 13 661
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