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Genetic and reproductive toxicity

Genetic toxicity and reproductive toxicity are central aspects of toxicological assessment. They examine the potential harmful effects of substances on the genome and the reproductive system. These evaluations are essential to assess the risk of genetic damage and reproductive impairment in a scientifically sound manner and in accordance with regulatory requirements.

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Our test portfolio for the following product groups:

Chemicals, agrochemicals, SVHC, biocides

Genetic toxicity

Bacterial reverse mutation test (AMES test) OECD 471
In vitro mammalian chromosomal aberration test OECD 473
In vitro mammalian cell gene mutation test using Hprt and xprt genes OECD 476
In vitro mammalian cell gene mutation test, Mouse Lymphoma Assay (MLA) OECD 490
Mammalian erythrocyte micronucleus test, in vivo OECD 474
In vitro mammalian cell micronucleus test OECD 487
In vivo mammalian Alkaline Comet Assay OECD 489
Prenatal development toxicity study in rat / rabbit OECD 414
Extended one generation oral or inhalation reproduction study in rat OECD 443
Screening test on reproduction / developmental toxicity in rat OECD 421
Screening test on combined repeated dose toxicity study on reproduction / developmental toxicity OECD 422